BiohacksAI/Mechanism Hypothesis/Homoharringtonine Semisynthetic derivative of harringtonine that acts as
Homoharringtonine Semisynthetic derivative of harringtonine that acts as — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
CYP3A4IFNGPMP22IFNB1YAP1HLA-BHTTHSF1PARP1POLY
10 known targets mapped from PubChem bioassay data
Pathway Context
Interferon Signaling3 targets overlapping
SARS-CoV Infections2 targets overlapping
Transcriptional regulation by RUNX12 targets overlapping
Uncovered Pathway Targets
193 totalATF6CAMK2BCAMK2DCASP1CDK1CHUKCHURC1-FNTBEIF2AK2EIF2AK3EIF4A1+183 more…
Genes present in the top pathway union that Homoharringtonine Semisynthetic derivative of harringtonine that acts as does not directly modulate.
Top Stack Candidates
Bortezomib
score 12,546.721#1 gap-filler · 44 targets covered · evidence score 44.2
PSMB8SNCATP53HDAC1HDAC2NFE2L2NFKB1NLRP3PSMC6RELASMAD3SYK+32
Colchicine
score 5,422.726#2 gap-filler · 25 targets covered · evidence score 42.1
PIM1TP53TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBA8TUBAL3TUBB1TUBB2A+13
639 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.