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Colchicine

A major alkaloid from Colchicum autumnale L. and found also in other Colchicum species. Its primary therapeutic use is in the treatment of gout, but it has been used also in the therapy of familial Mediterranean fever (PERIODIC DISEASE).

300+ PubMed studies analyzed · 13 RCTs · Evidence Score: 46.1

Research Domains

Colchicine has been studied across 20 research domains including 🔬 Inflammation, 🔬 Oncology, 🫁 Liver & Detox, ❤️ Cardiovascular, ⚡ Energy & Fatigue. The primary research focus is 🔬 Inflammation with 11% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Colchicine, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Nocodazole
51 shared targets
Podophyllotoxin
53 shared targets
Vincristine
41 shared targets
vinblastine
47 shared targets
Demecolcine
33 shared targets
Noscapine
23 shared targets
Vorinostat
27 shared targets
Melphalan
28 shared targets
Maytansine
16 shared targets
Emetine
25 shared targets
Loading evidence profile...

This evidence profile for Colchicine is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.