Hyoscyamine — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
CYP2D6CYP2C9CYTOCHROMECHRM1DRD1CHRM2HRH1CHRM5CHRM4CHRM3
10 known targets mapped from PubChem bioassay data
Pathway Context
Class A/1 (Rhodopsin-like receptors)7 targets overlapping
Amine ligand-binding receptors7 targets overlapping
Muscarinic acetylcholine receptors5 targets overlapping
Uncovered Pathway Targets
217 totalADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2+207 more…
Genes present in the top pathway union that Hyoscyamine does not directly modulate.
Top Stack Candidates
Aripiprazole
score 6,721.884#1 gap-filler · 32 targets covered · evidence score 52.0
ADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1AVPR1A+20
Astemizole Antihistamine drug now withdrawn from
score 6,222.149#2 gap-filler · 30 targets covered · evidence score 48.7
ADRA1AADRA2AADRA2CADRB2APLNRAVPR1ADRD2DRD3DRD4GALR2GHSRHRH2+18
932 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.