BiohacksAI/Mechanism Hypothesis/Secologanin Tryptamine Alkaloids Compounds formed by condensation of secologanin with tryptamine resulting in

Secologanin Tryptamine Alkaloids Compounds formed by condensation of secologanin with tryptamine resulting in — Mechanism Gap Analysis

HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal

Known Targets

CYP2C19ARCYP2C9ESR1CYTOCHROMECYP1A2ESRRANFE2L2GLI3PGRRATTUSRORCNUCLEARRARADRD3AHRCA4CA6

18 known targets mapped from PubChem bioassay data

Pathway Context

Nuclear Receptor transcription pathway5 targets overlapping

Biological oxidations4 targets overlapping

Phase I - Functionalization of compounds4 targets overlapping

Uncovered Pathway Targets

124 total

ESR2ESRRBESRRGHNF4AHNF4GNCOR1NCOR2NR0B1NR1D1NR1D2+114 more…

Genes present in the top pathway union that Secologanin Tryptamine Alkaloids Compounds formed by condensation of secologanin with tryptamine resulting in does not directly modulate.

Top Stack Candidates

Progesterone

#1 gap-filler · 19 targets covered · evidence score 50.6

score 4,574.276

ESR2ESRRGHNF4AHNF4GNR1H2NR1H4NR1I2NR2F1NR3C1NR3C2NR4A2NR5A1+7

Quercetin

#2 gap-filler · 19 targets covered · evidence score 43.4

score 3,434.897

NR1I2NR3C1PPARGRXRACYP19A1CYP1A1CYP1B1CYP2C8CYP3A4HSP90AB1MAOANNMT+7

755 more candidates · full stack optimisation locked

Enter your API token to unlock the complete analysis.

BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.