B

BiohacksAI

Evidence-Based Biohacking

Patent Pending
BiohacksAI/Mechanism Hypothesis/Lovastatin

Lovastatin — Mechanism Gap Analysis

HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal

Known Targets

CYP2C19CYP2D6ARCYP2C9NR1I2CYTOCHROMETDP1THRBESRRACYP3A4CYP3A7NFE2L2SYKTYROSINE-PROTEINCHAINGLI3RATTUSNSD2RORCMUSHISTONE-LYSINENR3C1ABCB1KCNH2RARAEUCHROMATICHOMOHTR2ACYP19A1VDRJUNSODIUM-DEPENDENTSTK33MDM2MDM4IDH1CASP3CASP7KCNMB2NFKB1NR0B1GAPDHKCNMA1TRHRSMN2RAC-ALPHASUBSTANCE-KSMARCA2HMGCRCHEK2ITGALSERINE-PROTEINCHURC1-FNTBFNTAFNTBICAM1ITGB2PGGT1B

58 known targets mapped from PubChem bioassay data

Pathway Context

SARS-CoV Infections8 targets overlapping
Nuclear Receptor transcription pathway7 targets overlapping
Biological oxidations6 targets overlapping

Uncovered Pathway Targets

165 total
AKT3ATP1A1ATP1A2ATP1A3ATP1A4ATP1B1ATP1B2ATP1B3BCL2L1BRD4+155 more…

Genes present in the top pathway union that Lovastatin does not directly modulate.

Top Stack Candidates

Progesterone

#1 gap-filler · 19 targets covered · evidence score 50.6

score 4,674.172
SIGMAR1ESR1ESR2ESRRGHNF4AHNF4GNR1H2NR1H4NR2F1NR3C2NR4A2NR5A1+7
Crizotinib

#2 gap-filler · 15 targets covered · evidence score 46.7

score 4,148.35
BTKHLA-BIFNB1IKBKBIKBKEIRAK1JAK3MAP3K7NPM1RIPK2ROCK2SRPK1+3

692 more candidates · full stack optimisation locked

Enter your API token to unlock the complete analysis.

BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.