Lutein — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
THRBTP53NR3C1RXRA
4 known targets mapped from PubChem bioassay data
Pathway Context
SUMOylation3 targets overlapping
SUMO E3 ligases SUMOylate target proteins3 targets overlapping
Nuclear Receptor transcription pathway2 targets overlapping
Uncovered Pathway Targets
76 totalARAURKAAURKBBIRC5BLMBRCA1CREBBPCTBP1DNMT1DNMT3B+66 more…
Genes present in the top pathway union that Lutein does not directly modulate.
Top Stack Candidates
Progesterone
score 4,610.883#1 gap-filler · 20 targets covered · evidence score 50.6
ARESR1NR1H2NR1H4NR1I2NR3C2NR4A2NR5A1NR5A2PGRRARARORA+8
Daunorubicin
score 3,060.033#2 gap-filler · 19 targets covered · evidence score 41.9
ARBLMESR1HDAC1HDAC2HDAC4HDAC7NR1H4NR1I2PARP1PGRPPARG+7
626 more candidates · full stack optimisation locked
Enter your API token to unlock the complete analysis.
BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.