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BiohacksAI/Mechanism Hypothesis/Mescaline Hallucinogenic alkaloid isolated from

Mescaline Hallucinogenic alkaloid isolated from — Mechanism Gap Analysis

HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal

Known Targets

5-HYDROXYTRYPTAMINEHTR2AHTR1AADRA2AHTR2BADRA2CHTR2CHTR7HTR6HTR1BHTR1DHTR5AHTR1FHTR1EHTR3AHTR3BNISCHHTR4HTR5B

19 known targets mapped from PubChem bioassay data

Pathway Context

Amine ligand-binding receptors10 targets overlapping
Serotonin receptors8 targets overlapping

Uncovered Pathway Targets

217 total
ADORA2BADORA3ADRA1AADRA1BADRA1DADRA2BADRB1ADRB2ADRB3AGTR1+207 more…

Genes present in the top pathway union that Mescaline Hallucinogenic alkaloid isolated from does not directly modulate.

Top Stack Candidates

Isoproterenol Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on

#1 gap-filler · 36 targets covered · evidence score 44.3

score 10,137.337
ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3DRD2DRD3DRD4TSHRCREB1GRK2+24
Aripiprazole

#2 gap-filler · 26 targets covered · evidence score 52.0

score 5,602.589
ADORA3ADRA1AADRA1BADRA1DADRA2BADRB1ADRB2ADRB3AGTR1AVPR1ACHRM1CHRM2+14

697 more candidates · full stack optimisation locked

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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.