Methandrostenolone — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
ARESR1TDP1ESRRACYP3A7NFE2L2GLI3PGRNSD2HISTONE-LYSINENR3C1ESR2
12 known targets mapped from PubChem bioassay data
Pathway Context
Nuclear Receptor transcription pathway6 targets overlapping
Transcriptional regulation by RUNX25 targets overlapping
SUMOylation4 targets overlapping
Uncovered Pathway Targets
124 totalESRRBESRRGHNF4AHNF4GNCOR1NCOR2NR0B1NR1D1NR1D2NR1H2+114 more…
Genes present in the top pathway union that Methandrostenolone does not directly modulate.
Top Stack Candidates
Bortezomib
score 12,431.87#1 gap-filler · 43 targets covered · evidence score 44.2
NR1I2PPARDRARAADRM1HDAC3PSMA1PSMA2PSMA3PSMA4PSMA5PSMA6PSMA7+31
Progesterone
score 4,562.353#2 gap-filler · 18 targets covered · evidence score 50.6
ESRRGHNF4AHNF4GNR1H2NR1H4NR1I2NR2F1NR3C2NR4A2NR5A1NR5A2RARA+6
561 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.