Methylcholanthrene — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
CYP2C19ARCYP2C9NR1I2ESR1CYTOCHROMECYP1A2THRBESRRACYP3A4NFE2L2PGRNUCLEARAHRMAPTCASP3HSPB1CASP7ADENOSINEATF6
20 known targets mapped from PubChem bioassay data
Pathway Context
Biological oxidations5 targets overlapping
Phase I - Functionalization of compounds5 targets overlapping
Cytochrome P450 - arranged by substrate type5 targets overlapping
Uncovered Pathway Targets
87 totalAADACAHCYALDH1A1ALDH2AOC1ARNTCBR3CES1CES2CYP11B1+77 more…
Genes present in the top pathway union that Methylcholanthrene does not directly modulate.
Top Stack Candidates
Progesterone
score 4,469.464#1 gap-filler · 18 targets covered · evidence score 50.6
CYP2D6NR1H4RXRAESR2ESRRGHNF4AHNF4GNR1H2NR2F1NR3C1NR3C2NR4A2+6
Aldosterone
score 2,987.08#2 gap-filler · 12 targets covered · evidence score 44.6
RXRAESRRGHNF4GNR1D1NR2C1NR3C1NR3C2NR4A2NR5A1NR5A2PPARARORB
656 more candidates · full stack optimisation locked
Enter your API token to unlock the complete analysis.
BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.