BiohacksAI/Mechanism Hypothesis/Mometasone Furoate

Mometasone Furoate — Mechanism Gap Analysis

HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal

Known Targets

CYP2C19CYP2D6ARCYP2C9NR1I2CYTOCHROMETDP1THRBESRRACYP3A4NFE2L2SYKTYROSINE-PROTEINPGRNSD2RORCHISTONE-LYSINENR3C1KCNH2RARACFTRNR1H4STK33IL1BANDROGENABCB11IDH1HIF1AADORA3CASP3GLUCOCORTICOIDHSPB1CASP7PPP1R15ASLCO1B1SLCO1B3PPP1CAATF6

38 known targets mapped from PubChem bioassay data

Pathway Context

Nuclear Receptor transcription pathway7 targets overlapping

Drug ADME6 targets overlapping

SUMOylation6 targets overlapping

Uncovered Pathway Targets

113 total

ESR1ESR2ESRRBESRRGHNF4AHNF4GNCOR1NCOR2NR0B1NR1D1+103 more…

Genes present in the top pathway union that Mometasone Furoate does not directly modulate.

Top Stack Candidates

Progesterone

#1 gap-filler · 20 targets covered · evidence score 50.6

score 5,056.474

ESR1ESR2ESRRGHNF4AHNF4GNR1H2NR2F1NR3C2NR4A2NR5A1NR5A2RARB+8

Quercetin

#2 gap-filler · 17 targets covered · evidence score 43.4

score 3,393.329

ESR1PPARGRXRAABCB1ABCC1ABCG2CYP2C8PON1SLCO2B1XDHAURKBBLM+5

660 more candidates · full stack optimisation locked

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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.