BiohacksAI/Mechanism Hypothesis/Nitrofurazone

Nitrofurazone — Mechanism Gap Analysis

HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal

Known Targets

CYP2C19CYP2D6ARNR1I2ESR1CYTOCHROMETDP1CYP1A2ESRRACYP3A7NFE2L2SYKTYROSINE-PROTEINGLI3NSD2RORCHISTONE-LYSINECYP19A1AHRIFNGTSHRPMP22RXRATXNRD1IP6K1GPT2HCRTR1

27 known targets mapped from PubChem bioassay data

Pathway Context

Biological oxidations7 targets overlapping

Phase I - Functionalization of compounds7 targets overlapping

Cytochrome P450 - arranged by substrate type7 targets overlapping

Uncovered Pathway Targets

86 total

AADACAHCYALDH1A1ALDH2AOC1ARNTCBR3CES1CES2CYP11B1+76 more…

Genes present in the top pathway union that Nitrofurazone does not directly modulate.

Top Stack Candidates

Progesterone

#1 gap-filler · 18 targets covered · evidence score 50.6

score 4,409.873

CYP2C9NR1H4ESR2ESRRGHNF4AHNF4GNR1H2NR2F1NR3C1NR3C2NR4A2NR5A1+6

Aldosterone

#2 gap-filler · 12 targets covered · evidence score 44.6

score 2,930.373

ESRRGHNF4GNR1D1NR2C1NR3C1NR3C2NR4A2NR5A1NR5A2PGRPPARARORB

603 more candidates · full stack optimisation locked

Enter your API token to unlock the complete analysis.

BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.