Novobiocin — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
IFNGHSP90AA1HSP90AB1MAP1LC3AMAP1LC3B
5 known targets mapped from PubChem bioassay data
Pathway Context
Autophagy4 targets overlapping
SARS-CoV Infections3 targets overlapping
Macroautophagy3 targets overlapping
Uncovered Pathway Targets
129 totalATG4BATMCFTRCSNK2A1CSNK2A2CSNK2BEPAS1HBBHDAC6HSPA8+119 more…
Genes present in the top pathway union that Novobiocin does not directly modulate.
Top Stack Candidates
Colchicine
score 4,997.303#1 gap-filler · 22 targets covered · evidence score 42.1
TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBA8TUBAL3TUBB1TUBB2ATUBB2BTUBB3+10
Nocodazole Nocodazole is
score 4,959.657#2 gap-filler · 22 targets covered · evidence score 42.9
CFTRTUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBA8TUBAL3TUBB1TUBB2ATUBB2B+10
550 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.