Nylidrin — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
CYP2C19CYP2D6CYP1A2CYP3A7KCNH2DRD35-HYDROXYTRYPTAMINEADRA1ADRD2HTR1AADRA2AADRB2HTR2BADRA2CJUNADRA2BSLC6A3MU-TYPEKAPPA-TYPEADRB1
20 known targets mapped from PubChem bioassay data
Pathway Context
Class A/1 (Rhodopsin-like receptors)10 targets overlapping
Amine ligand-binding receptors10 targets overlapping
Adrenoceptors6 targets overlapping
Uncovered Pathway Targets
189 totalADORA2BADORA3ADRA1BADRA1DADRB3AGTR1AGTR2APLNRAPPAVPR1A+179 more…
Genes present in the top pathway union that Nylidrin does not directly modulate.
Top Stack Candidates
Astemizole Antihistamine drug now withdrawn from
score 5,557.731#1 gap-filler · 26 targets covered · evidence score 48.7
APLNRAVPR1ACHRM1CHRM2CHRM3DRD1DRD4GALR2GHSRHRH1HRH2HRH4+14
Aripiprazole
score 5,165.05#2 gap-filler · 24 targets covered · evidence score 52.0
ADORA3ADRA1BADRA1DADRB3AGTR1AVPR1ACHRM1CHRM2DRD1DRD4DRD5HRH1+12
841 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.