Pravastatin — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
HOMOSLCO1B1SLCO2B1HMGCR
4 known targets mapped from PubChem bioassay data
Pathway Context
Drug ADME2 targets overlapping
Atorvastatin ADME2 targets overlapping
Metabolism of steroids2 targets overlapping
Uncovered Pathway Targets
131 totalABCB1ABCC1ABCC2ABCC3ABCC4ABCC5ABCG2ADAADKAKR1C1+121 more…
Genes present in the top pathway union that Pravastatin does not directly modulate.
Top Stack Candidates
Clotrimazole
score 2,749.696#1 gap-filler · 14 targets covered · evidence score 48.8
ABCB1CYP2C19CYP2C8CYP2C9CYP2D6CYP3A4ABCB11CYP17A1CYP19A1CYP51A1CYP8B1NR1H4+2
Simvastatin
score 2,465.537#2 gap-filler · 11 targets covered · evidence score 71.8
ABCB1CYP2C19CYP2C8CYP2C9CYP2D6CYP3A4ABCB11CYP19A1NR1H4SLC6A2SLC6A3
819 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.