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Clotrimazole

An imidazole derivative with a broad spectrum of antimycotic activity. It inhibits biosynthesis of the sterol ergostol, an important component of fungal CELL MEMBRANES. Its action leads to increased membrane permeability and apparent disruption of enzyme systems bound to the membrane.

296+ PubMed studies analyzed · 53 RCTs · Evidence Score: 48.3

Research Domains

Clotrimazole has been studied across 14 research domains including 🫁 Liver & Detox, 🔬 Oncology, ✨ Skin & Hair, 🛡️ Immunity, 🔥 Metabolic. The primary research focus is 🫁 Liver & Detox with 9% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Clotrimazole, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Miconazole
51 shared targets
Econazole
35 shared targets
Loratadine
45 shared targets
Astemizole
56 shared targets
Danazol
37 shared targets
Hexachlorophene
61 shared targets
Nisoldipine
46 shared targets
Troglitazone
39 shared targets
17
32 shared targets
Ethinyl
40 shared targets
Loading evidence profile...

This evidence profile for Clotrimazole is generated deterministically from 296 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.