Probenecid — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
ARESR1CA2CA12CA9SLC22A8TRPA1SLC22A6TRANSIENTPANX1SLC22A20
11 known targets mapped from PubChem bioassay data
Pathway Context
Reversible hydration of carbon dioxide3 targets overlapping
SUMOylation2 targets overlapping
SUMO E3 ligases SUMOylate target proteins2 targets overlapping
Uncovered Pathway Targets
86 totalCA1CA13CA14CA3CA4CA5ACA5BCA6CA7AURKA+76 more…
Genes present in the top pathway union that Probenecid does not directly modulate.
Top Stack Candidates
Progesterone
score 4,862.151#1 gap-filler · 21 targets covered · evidence score 50.6
NR1H2NR1H4NR1I2NR3C1NR3C2NR4A2NR5A1NR5A2PGRRARARORARXRA+9
Bortezomib
score 3,953.496#2 gap-filler · 22 targets covered · evidence score 44.2
CA1CA13CA14CA3CA4CA5ACA5BCA6CA7HDAC1HDAC2MITF+10
643 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.