Secretin — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
ADCYAP1R1SCTRVIPR1VIPR2
4 known targets mapped from PubChem bioassay data
Pathway Context
G alpha (s) signalling events3 targets overlapping
Class B/2 (Secretin family receptors)3 targets overlapping
Glucagon-type ligand receptors3 targets overlapping
Uncovered Pathway Targets
59 totalADCY9ADORA2BADRB1ADRB2ADRB3ARRB1AVPR2CALCRCRHR1CYSLTR2+49 more…
Genes present in the top pathway union that Secretin does not directly modulate.
Top Stack Candidates
Papaverine
score 2,298.321#1 gap-filler · 8 targets covered · evidence score 45.1
PDE10APDE1APDE1BPDE2APDE3APDE3BPDE4APDE4D
Aripiprazole
score 2,133.002#2 gap-filler · 10 targets covered · evidence score 52.0
ADRB1ADRB2ADRB3DRD1DRD5GPR32HRH2HTR6HTR7TAAR1
398 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.