Strychnine — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
KCNH2CHRM1CHRM2CHRM5CHRM4CHRM3GLRA1CHRNA10CHRNA9GLRA2GLYCINETAS2R10TAS2R46GLRA3GLRB
15 known targets mapped from PubChem bioassay data
Pathway Context
Class A/1 (Rhodopsin-like receptors)5 targets overlapping
Neuronal System5 targets overlapping
Amine ligand-binding receptors5 targets overlapping
Uncovered Pathway Targets
325 totalADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2+315 more…
Genes present in the top pathway union that Strychnine does not directly modulate.
Top Stack Candidates
Isoproterenol Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on
score 9,512.965#1 gap-filler · 34 targets covered · evidence score 44.3
ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3DRD2DRD3DRD4TSHRCREB1GRK2+22
Aripiprazole
score 9,182.212#2 gap-filler · 42 targets covered · evidence score 52.0
ADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1AVPR1A+30
797 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.