Trapidil — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
ARCYP1A2CYP3A7RAPGEF4RAPGEF3
5 known targets mapped from PubChem bioassay data
Pathway Context
Biological oxidations2 targets overlapping
Phase I - Functionalization of compounds2 targets overlapping
Cytochrome P450 - arranged by substrate type2 targets overlapping
Uncovered Pathway Targets
184 totalAADACAHCYAHRALDH1A1ALDH2AOC1ARNTCBR3CES1CES2+174 more…
Genes present in the top pathway union that Trapidil does not directly modulate.
Top Stack Candidates
Colchicine
score 4,757.527#1 gap-filler · 23 targets covered · evidence score 42.1
CYP2C19CYP2C9CYP2D6NR1H4SYKTP53TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4A+11
Nocodazole Nocodazole is
score 4,733.103#2 gap-filler · 22 targets covered · evidence score 42.9
AHRCYP2D6NR1H4ABL1SYKTP53TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4A+10
841 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.