B

BiohacksAI

Evidence-Based Biohacking

Patent Pending
BiohacksAI/Mechanism Hypothesis/Triiodothyronine

Triiodothyronine — Mechanism Gap Analysis

HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal

Known Targets

CYP2C19CYP2D6CYP2C9ESR1CYTOCHROMETHRBCYP3A4CHAINPGRRATTUSRORCMUSTP53NR3C1RARAHOMOAHRPPARGNNMTPNMTGAMTGNMTHNMTCATECHOLNR5A1SLCO1B1GPX4PHOSPHOLIPIDADENOSINENR5A2NPY1RSLCO1B3TTRTHYROIDADORA1GABRA1GABRA2GABRA3GABRA4GABRB2GABRB3GABRG2GABRA5GABRA6GABRB1GABRDGABREGABRG1GABRG3GABRPSLCO1A5HNF4APROTHROMBINSLCO1A2SLCO4C1NR4A2RORAGABASLCO1A4ESRRGRARBTHRAPCNASLCO4A1

64 known targets mapped from PubChem bioassay data

Pathway Context

Nuclear Receptor transcription pathway13 targets overlapping
SUMOylation12 targets overlapping
SUMO E3 ligases SUMOylate target proteins12 targets overlapping

Uncovered Pathway Targets

193 total
ARESR2ESRRAESRRBHNF4GNCOR1NCOR2NR0B1NR1D1NR1D2+183 more…

Genes present in the top pathway union that Triiodothyronine does not directly modulate.

Top Stack Candidates

Colchicine

#1 gap-filler · 28 targets covered · evidence score 42.1

score 6,012.775
ARESRRANR0B1NR1H4NR1I2VDRBRCA1CREBBPMDM2GLRA1GLRA2TUBA1A+16
Nocodazole Nocodazole is

#2 gap-filler · 28 targets covered · evidence score 42.9

score 5,876.468
ARESRRANR0B1NR1H4NR1I2VDRBRCA1CREBBPMDM2MITFPARP1CREB1+16

781 more candidates · full stack optimisation locked

Enter your API token to unlock the complete analysis.

BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.