Vortioxetine — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
SYKTYROSINE-PROTEINNSD2HISTONE-LYSINE5-HYDROXYTRYPTAMINEHTR2AHTR1APTGS1SLC6A4SODIUM-DEPENDENTPTGS2HTR7HTR6HTR1BHTR1DHTR5AHTR3A
17 known targets mapped from PubChem bioassay data
Pathway Context
Class A/1 (Rhodopsin-like receptors)4 targets overlapping
Amine ligand-binding receptors4 targets overlapping
Serotonin receptors4 targets overlapping
Uncovered Pathway Targets
411 totalADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2+401 more…
Genes present in the top pathway union that Vortioxetine does not directly modulate.
Top Stack Candidates
Bortezomib
score 12,283.384#1 gap-filler · 42 targets covered · evidence score 44.2
ADRM1CA1CREB1CTSGHIF1AIFNGNFKB1NFKB2PSMA1PSMA2PSMA3PSMA4+30
Aripiprazole
score 8,258.211#2 gap-filler · 38 targets covered · evidence score 52.0
ADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1AVPR1A+26
925 more candidates · full stack optimisation locked
Enter your API token to unlock the complete analysis.
BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.