Activation of caspases through apoptosome-mediated cleavage
REACTOME PATHWAYThe Activation of caspases through apoptosome-mediated cleavage pathway (Reactome ID: R-HSA-111459) involves 1 genes and is affected by 2 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Activation of caspases through apoptosome-mediated cleavage
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Methylene Blue | — | 200 |
| 2 | felbinac | — | 31 |
About the Activation of caspases through apoptosome-mediated cleavage Pathway
The Activation of caspases through apoptosome-mediated cleavage pathway is catalogued in Reactome (ID: R-HSA-111459) and involves 1 genes. In the BiohacksAI corpus, 2 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CASP9.