B

BiohacksAI

Evidence-Based Biohacking

Patent Pending

SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes

REACTOME PATHWAY
Reactome: R-HSA-1114641 genes2 compounds

The SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes pathway (Reactome ID: R-HSA-111464) involves 1 genes and is affected by 2 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

CASP9

Compounds Affecting SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes

#CompoundTargets HitStudies
1Methylene Blue—200
2felbinac—31

About the SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes Pathway

The SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes pathway is catalogued in Reactome (ID: R-HSA-111464) and involves 1 genes. In the BiohacksAI corpus, 2 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CASP9.