Intrinsic Pathway of Fibrin Clot Formation
REACTOME PATHWAYThe Intrinsic Pathway of Fibrin Clot Formation pathway (Reactome ID: R-HSA-140837) involves 3 genes and is affected by 4 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Intrinsic Pathway of Fibrin Clot Formation
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Gabexate | — | 300 |
| 2 | Rivaroxaban | — | 999 |
| 3 | apixaban [Supplementary Concept] | — | 997 |
| 4 | Bortezomib | — | 300 |
About the Intrinsic Pathway of Fibrin Clot Formation Pathway
The Intrinsic Pathway of Fibrin Clot Formation pathway is catalogued in Reactome (ID: R-HSA-140837) and involves 3 genes. In the BiohacksAI corpus, 4 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include F10, F12, KLKB1.