Formation of Fibrin Clot (Clotting Cascade)
REACTOME PATHWAYThe Formation of Fibrin Clot (Clotting Cascade) pathway (Reactome ID: R-HSA-140877) involves 6 genes and is affected by 7 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Formation of Fibrin Clot (Clotting Cascade)
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Gabexate | — | 300 |
| 2 | apixaban [Supplementary Concept] | — | 997 |
| 3 | Rivaroxaban | — | 999 |
| 4 | Bortezomib | — | 300 |
| 5 | trichostatic acid [Supplementary Concept] related to trichostatin | — | 300 |
| 6 | Oleanolic Acid | — | 300 |
| 7 | Cerulenin | — | 300 |
About the Formation of Fibrin Clot (Clotting Cascade) Pathway
The Formation of Fibrin Clot (Clotting Cascade) pathway is catalogued in Reactome (ID: R-HSA-140877) and involves 6 genes. In the BiohacksAI corpus, 7 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include F10, F12, F13A1, F3, F5.