Alpha-defensins
REACTOME PATHWAYThe Alpha-defensins pathway (Reactome ID: R-HSA-1462054) involves 2 genes and is affected by 2 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Alpha-defensins
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Bortezomib | — | 300 |
| 2 | Sulfaguanidine | — | 255 |
About the Alpha-defensins Pathway
The Alpha-defensins pathway is catalogued in Reactome (ID: R-HSA-1462054) and involves 2 genes. In the BiohacksAI corpus, 2 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include PRSS2, PRSS3.