Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
REACTOME PATHWAYThe Gamma-carboxylation, transport, and amino-terminal cleavage of proteins pathway (Reactome ID: R-HSA-159854) involves 3 genes and is affected by 6 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Rivaroxaban | — | 999 |
| 2 | apixaban [Supplementary Concept] | — | 997 |
| 3 | Gabexate | — | 300 |
| 4 | Diminazene | — | 300 |
| 5 | silver sulfadiazine | — | 299 |
| 6 | Vitamin K 2 | — | 300 |
About the Gamma-carboxylation, transport, and amino-terminal cleavage of proteins Pathway
The Gamma-carboxylation, transport, and amino-terminal cleavage of proteins pathway is catalogued in Reactome (ID: R-HSA-159854) and involves 3 genes. In the BiohacksAI corpus, 6 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include F10, FURIN, GGCX.