Heparan sulfate/heparin (HS-GAG) metabolism
REACTOME PATHWAYThe Heparan sulfate/heparin (HS-GAG) metabolism pathway (Reactome ID: R-HSA-1638091) involves 2 genes and is affected by 6 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Heparan sulfate/heparin (HS-GAG) metabolism
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Hesperidin | — | 300 |
| 2 | naringin | — | 300 |
| 3 | Astemizole Antihistamine drug now withdrawn from | — | 280 |
| 4 | Labetalol | — | 295 |
| 5 | Metergoline | — | 144 |
| 6 | Triamcinolone | — | 300 |
About the Heparan sulfate/heparin (HS-GAG) metabolism Pathway
The Heparan sulfate/heparin (HS-GAG) metabolism pathway is catalogued in Reactome (ID: R-HSA-1638091) and involves 2 genes. In the BiohacksAI corpus, 6 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CTSL, HPSE.