Activation of AKT2
REACTOME PATHWAYThe Activation of AKT2 pathway (Reactome ID: R-HSA-165158) involves 1 genes and is affected by 3 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Activation of AKT2
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | sp600125 | — | 117 |
| 2 | alsterpaullone | — | 12 |
| 3 | kenpaullone | — | 8 |
About the Activation of AKT2 Pathway
The Activation of AKT2 pathway is catalogued in Reactome (ID: R-HSA-165158) and involves 1 genes. In the BiohacksAI corpus, 3 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include PDPK1.