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BiohacksAI

Evidence-Based Biohacking

Patent Pending

Signaling by FGFR2 amplification mutants

REACTOME PATHWAY
Reactome: R-HSA-20238371 genes3 compounds

The Signaling by FGFR2 amplification mutants pathway (Reactome ID: R-HSA-2023837) involves 1 genes and is affected by 3 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

FGFR2

Compounds Affecting Signaling by FGFR2 amplification mutants

#CompoundTargets HitStudies
1Sorafenib—300
2Axitinib—298
3Dasatinib—299

About the Signaling by FGFR2 amplification mutants Pathway

The Signaling by FGFR2 amplification mutants pathway is catalogued in Reactome (ID: R-HSA-2023837) and involves 1 genes. In the BiohacksAI corpus, 3 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include FGFR2.