HS-GAG degradation
REACTOME PATHWAYThe HS-GAG degradation pathway (Reactome ID: R-HSA-2024096) involves 2 genes and is affected by 6 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting HS-GAG degradation
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Hesperidin | — | 300 |
| 2 | naringin | — | 300 |
| 3 | Astemizole Antihistamine drug now withdrawn from | — | 280 |
| 4 | Labetalol | — | 295 |
| 5 | Metergoline | — | 144 |
| 6 | Triamcinolone | — | 300 |
About the HS-GAG degradation Pathway
The HS-GAG degradation pathway is catalogued in Reactome (ID: R-HSA-2024096) and involves 2 genes. In the BiohacksAI corpus, 6 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CTSL, HPSE.