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BiohacksAI

Evidence-Based Biohacking

Patent Pending

Hypusine synthesis from eIF5A-lysine

REACTOME PATHWAY
Reactome: R-HSA-2046261 genes2 compounds

The Hypusine synthesis from eIF5A-lysine pathway (Reactome ID: R-HSA-204626) involves 1 genes and is affected by 2 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

DOHH

Compounds Affecting Hypusine synthesis from eIF5A-lysine

#CompoundTargets HitStudies
1Deferoxamine Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as—296
2Mimosine 3-Hydroxy-4-oxo-1(4H)-pyridinealanine.—300

About the Hypusine synthesis from eIF5A-lysine Pathway

The Hypusine synthesis from eIF5A-lysine pathway is catalogued in Reactome (ID: R-HSA-204626) and involves 1 genes. In the BiohacksAI corpus, 2 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include DOHH.