Diseases of glycosylation
REACTOME PATHWAYThe Diseases of glycosylation pathway (Reactome ID: R-HSA-3781865) involves 8 genes and is affected by 17 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Diseases of glycosylation
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | egcg | — | 300 |
| 2 | streptonigrin | — | 299 |
| 3 | piceatannol | — | 300 |
| 4 | caffeic acid | — | 300 |
| 5 | Rutin | — | 300 |
| 6 | Metergoline | — | 144 |
| 7 | Methyldopa | — | 297 |
| 8 | Oxytetracycline | — | 300 |
| 9 | Tolazamide | — | 169 |
| 10 | Hexachlorophene | — | 300 |
| 11 | Quercetin | — | 300 |
| 12 | Aurintricarboxylic Acid | — | 184 |
| 13 | Luteolin 5,7,3',4'-tetrahydroxy-flavone, | — | 150 |
| 14 | Apigenin 5,7,4'-trihydroxy-flavone, | — | 300 |
| 15 | Methylene Blue | — | 200 |
| 16 | Bortezomib | — | 300 |
| 17 | urolithin d | — | 2 |
About the Diseases of glycosylation Pathway
The Diseases of glycosylation pathway is catalogued in Reactome (ID: R-HSA-3781865) and involves 8 genes. In the BiohacksAI corpus, 17 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include ADAMTS4, ADAMTS5, CTSA, GALK1, GALNT3.