Mitochondrial tRNA aminoacylation
REACTOME PATHWAYThe Mitochondrial tRNA aminoacylation pathway (Reactome ID: R-HSA-379726) involves 2 genes and is affected by 2 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Mitochondrial tRNA aminoacylation
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Chloramphenicol | — | 297 |
| 2 | methyl 13-(alpha-naphthalene)aminodeisopropyldehydroabietate [Supplementary Concept] | — | 161 |
About the Mitochondrial tRNA aminoacylation Pathway
The Mitochondrial tRNA aminoacylation pathway is catalogued in Reactome (ID: R-HSA-379726) and involves 2 genes. In the BiohacksAI corpus, 2 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include KARS1, MARS2.