Receptor-type tyrosine-protein phosphatases
REACTOME PATHWAYThe Receptor-type tyrosine-protein phosphatases pathway (Reactome ID: R-HSA-388844) involves 3 genes and is affected by 5 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Receptor-type tyrosine-protein phosphatases
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Sorafenib | — | 300 |
| 2 | Crizotinib | — | 298 |
| 3 | sp600125 | — | 117 |
| 4 | Ursolic Acid | — | 300 |
| 5 | scutellarein | — | 113 |
About the Receptor-type tyrosine-protein phosphatases Pathway
The Receptor-type tyrosine-protein phosphatases pathway is catalogued in Reactome (ID: R-HSA-388844) and involves 3 genes. In the BiohacksAI corpus, 5 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include NTRK3, PTPRF, PTPRS.