Orexin and neuropeptides FF and QRFP bind to their respective receptors
REACTOME PATHWAYThe Orexin and neuropeptides FF and QRFP bind to their respective receptors pathway (Reactome ID: R-HSA-389397) involves 1 genes and is affected by 15 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Orexin and neuropeptides FF and QRFP bind to their respective receptors
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Furazolidone | — | 300 |
| 2 | Hexachlorophene | — | 300 |
| 3 | Miconazole | — | 298 |
| 4 | Niridazole | — | 300 |
| 5 | Methylene Blue | — | 200 |
| 6 | Calcimycin | — | 216 |
| 7 | Carvedilol | — | 296 |
| 8 | Dinitrochlorobenzene | — | 300 |
| 9 | Fluspirilene | — | 74 |
| 10 | Niclosamide | — | 299 |
| 11 | Nitrofurantoin | — | 297 |
| 12 | Nitrofurazone | — | 300 |
| 13 | rafoxanide | — | 172 |
| 14 | Rimonabant | — | 300 |
| 15 | tyrphostin 9 | — | 2 |
About the Orexin and neuropeptides FF and QRFP bind to their respective receptors Pathway
The Orexin and neuropeptides FF and QRFP bind to their respective receptors pathway is catalogued in Reactome (ID: R-HSA-389397) and involves 1 genes. In the BiohacksAI corpus, 15 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include HCRTR1.