ADP signalling through P2Y purinoceptor 12
REACTOME PATHWAYThe ADP signalling through P2Y purinoceptor 12 pathway (Reactome ID: R-HSA-392170) involves 2 genes and is affected by 21 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting ADP signalling through P2Y purinoceptor 12
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Aurintricarboxylic Acid | — | 184 |
| 2 | Daunorubicin | — | 298 |
| 3 | Ethidium | — | 300 |
| 4 | Apigenin 5,7,4'-trihydroxy-flavone, | — | 300 |
| 5 | Rosmarinic Acid | — | 300 |
| 6 | Allantoin | — | 300 |
| 7 | Diiodotyrosine | — | 300 |
| 8 | Dimethylphenylpiperazinium Iodide | — | 33 |
| 9 | Dipyrone | — | 298 |
| 10 | Idarubicin | — | 299 |
| 11 | iodoform | — | 272 |
| 12 | Nicergoline | — | 300 |
| 13 | Pseudoephedrine | — | 298 |
| 14 | Riboflavin Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. | — | 297 |
| 15 | tiopronin | — | 299 |
| 16 | tyrphostin ag 1478 | — | 4 |
| 17 | Ticagrelor | — | 299 |
| 18 | Adenosine Diphosphate Adenosine 5'-(trihydrogen diphosphate). | — | 300 |
| 19 | Adenosine Triphosphate | — | 300 |
| 20 | Leukotriene E4 | — | 300 |
| 21 | Suramin | — | 300 |
About the ADP signalling through P2Y purinoceptor 12 Pathway
The ADP signalling through P2Y purinoceptor 12 pathway is catalogued in Reactome (ID: R-HSA-392170) and involves 2 genes. In the BiohacksAI corpus, 21 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include GNAI1, P2RY12.