Prostacyclin signalling through prostacyclin receptor
REACTOME PATHWAYThe Prostacyclin signalling through prostacyclin receptor pathway (Reactome ID: R-HSA-392851) involves 2 genes and is affected by 8 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Prostacyclin signalling through prostacyclin receptor
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Iloprost | — | 300 |
| 2 | Alprostadil | — | 297 |
| 3 | Dinoprostone | — | 296 |
| 4 | Epoprostenol | — | 297 |
| 5 | Niclosamide | — | 299 |
| 6 | Tetraethylammonium | — | 119 |
| 7 | Triacetin | — | 300 |
| 8 | urolithin b | — | 49 |
About the Prostacyclin signalling through prostacyclin receptor Pathway
The Prostacyclin signalling through prostacyclin receptor pathway is catalogued in Reactome (ID: R-HSA-392851) and involves 2 genes. In the BiohacksAI corpus, 8 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include GNAS, PTGIR.