Activation of AMPA receptors
REACTOME PATHWAYThe Activation of AMPA receptors pathway (Reactome ID: R-HSA-399710) involves 4 genes and is affected by 6 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Activation of AMPA receptors
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Glutamic Acid | — | 297 |
| 2 | Glutamic Acid | — | 300 |
| 3 | alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid | — | 300 |
| 4 | aniracetam | — | 110 |
| 5 | Piracetam | — | 300 |
| 6 | Riluzole | — | 298 |
About the Activation of AMPA receptors Pathway
The Activation of AMPA receptors pathway is catalogued in Reactome (ID: R-HSA-399710) and involves 4 genes. In the BiohacksAI corpus, 6 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include GRIA1, GRIA2, GRIA3, GRIA4.