Ca2+ pathway
REACTOME PATHWAYThe Ca2+ pathway pathway (Reactome ID: R-HSA-4086398) involves 7 genes and is affected by 12 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Ca2+ pathway
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Sorafenib | — | 300 |
| 2 | Adenosine | — | 298 |
| 3 | Adenosine Diphosphate Adenosine 5'-(trihydrogen diphosphate). | — | 300 |
| 4 | Adenosine Triphosphate | — | 300 |
| 5 | Crizotinib | — | 298 |
| 6 | Cefixime | — | 300 |
| 7 | Emtricitabine | — | 292 |
| 8 | Dasatinib | — | 299 |
| 9 | egcg | — | 300 |
| 10 | Antazoline | — | 229 |
| 11 | pnu74654 | — | 6 |
| 12 | Sulfisomidine | — | 73 |
About the Ca2+ pathway Pathway
The Ca2+ pathway pathway is catalogued in Reactome (ID: R-HSA-4086398) and involves 7 genes. In the BiohacksAI corpus, 12 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include AGO2, GNAO1, MAP3K7, NLK, PDE6A.