Activation of RAC1
REACTOME PATHWAYThe Activation of RAC1 pathway (Reactome ID: R-HSA-428540) involves 4 genes and is affected by 3 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Activation of RAC1
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | kenpaullone | — | 8 |
| 2 | alsterpaullone | — | 12 |
| 3 | Axitinib | — | 298 |
About the Activation of RAC1 Pathway
The Activation of RAC1 pathway is catalogued in Reactome (ID: R-HSA-428540) and involves 4 genes. In the BiohacksAI corpus, 3 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include BUB1B-PAK6, PAK4, PAK5, PAK6.