O-linked glycosylation
REACTOME PATHWAYThe O-linked glycosylation pathway (Reactome ID: R-HSA-5173105) involves 10 genes and is affected by 6 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting O-linked glycosylation
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | urolithin d | — | 2 |
| 2 | egcg | — | 300 |
| 3 | piceatannol | — | 300 |
| 4 | Luteolin 5,7,3',4'-tetrahydroxy-flavone, | — | 150 |
| 5 | Apigenin 5,7,4'-trihydroxy-flavone, | — | 300 |
| 6 | Methylene Blue | — | 200 |
About the O-linked glycosylation Pathway
The O-linked glycosylation pathway is catalogued in Reactome (ID: R-HSA-5173105) and involves 10 genes. In the BiohacksAI corpus, 6 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include ADAMTS4, ADAMTS5, GALNT1, GALNT10, GALNT14.