Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
REACTOME PATHWAYThe Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) pathway (Reactome ID: R-HSA-5358565) involves 1 genes and is affected by 2 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Oleanolic Acid | — | 300 |
| 2 | Triiodothyronine | — | 300 |
About the Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) Pathway
The Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) pathway is catalogued in Reactome (ID: R-HSA-5358565) and involves 1 genes. In the BiohacksAI corpus, 2 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include PCNA.