Phospholipase C-mediated cascade; FGFR3
REACTOME PATHWAYThe Phospholipase C-mediated cascade; FGFR3 pathway (Reactome ID: R-HSA-5654227) involves 1 genes and is affected by 5 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Phospholipase C-mediated cascade; FGFR3
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Sorafenib | — | 300 |
| 2 | Axitinib | — | 298 |
| 3 | Crizotinib | — | 298 |
| 4 | Dasatinib | — | 299 |
| 5 | sp600125 | — | 117 |
About the Phospholipase C-mediated cascade; FGFR3 Pathway
The Phospholipase C-mediated cascade; FGFR3 pathway is catalogued in Reactome (ID: R-HSA-5654227) and involves 1 genes. In the BiohacksAI corpus, 5 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include FGFR3.