Defective ABCC8 can cause hypo- and hyper-glycemias
REACTOME PATHWAYThe Defective ABCC8 can cause hypo- and hyper-glycemias pathway (Reactome ID: R-HSA-5683177) involves 1 genes and is affected by 3 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Defective ABCC8 can cause hypo- and hyper-glycemias
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Cromakalim | — | 300 |
| 2 | Chlorpropamide | — | 300 |
| 3 | Glyburide | — | 298 |
About the Defective ABCC8 can cause hypo- and hyper-glycemias Pathway
The Defective ABCC8 can cause hypo- and hyper-glycemias pathway is catalogued in Reactome (ID: R-HSA-5683177) and involves 1 genes. In the BiohacksAI corpus, 3 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include ABCC8.