Sensing of DNA Double Strand Breaks
REACTOME PATHWAYThe Sensing of DNA Double Strand Breaks pathway (Reactome ID: R-HSA-5693548) involves 1 genes and is affected by 2 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Sensing of DNA Double Strand Breaks
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Methylene Blue | — | 200 |
| 2 | streptonigrin | — | 299 |
About the Sensing of DNA Double Strand Breaks Pathway
The Sensing of DNA Double Strand Breaks pathway is catalogued in Reactome (ID: R-HSA-5693548) and involves 1 genes. In the BiohacksAI corpus, 2 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include ATM.