Pyrimidine salvage
REACTOME PATHWAYThe Pyrimidine salvage pathway (Reactome ID: R-HSA-73614) involves 3 genes and is affected by 10 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Pyrimidine salvage
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Deoxycytidine | — | 300 |
| 2 | Gemcitabine | — | 300 |
| 3 | Cladribine | — | 297 |
| 4 | Cytarabine | — | 297 |
| 5 | Cytidine | — | 300 |
| 6 | Bromodeoxyuridine | — | 300 |
| 7 | Thymidine Monophosphate 5-Thymidylic acid. | — | 202 |
| 8 | Vidarabine | — | 299 |
| 9 | Tetrahydrouridine | — | 166 |
| 10 | Uridine | — | 300 |
About the Pyrimidine salvage Pathway
The Pyrimidine salvage pathway is catalogued in Reactome (ID: R-HSA-73614) and involves 3 genes. In the BiohacksAI corpus, 10 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CDA, DCK, TK1.