Signaling by plasma membrane FGFR1 fusions
REACTOME PATHWAYThe Signaling by plasma membrane FGFR1 fusions pathway (Reactome ID: R-HSA-8853336) involves 1 genes and is affected by 5 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Signaling by plasma membrane FGFR1 fusions
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Sorafenib | — | 300 |
| 2 | Axitinib | — | 298 |
| 3 | alsterpaullone | — | 12 |
| 4 | Dasatinib | — | 299 |
| 5 | sp600125 | — | 117 |
About the Signaling by plasma membrane FGFR1 fusions Pathway
The Signaling by plasma membrane FGFR1 fusions pathway is catalogued in Reactome (ID: R-HSA-8853336) and involves 1 genes. In the BiohacksAI corpus, 5 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include FGFR1.