Noncanonical activation of NOTCH3
REACTOME PATHWAYThe Noncanonical activation of NOTCH3 pathway (Reactome ID: R-HSA-9017802) involves 6 genes and is affected by 1 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Noncanonical activation of NOTCH3
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Dihydroergocristine | — | 187 |
About the Noncanonical activation of NOTCH3 Pathway
The Noncanonical activation of NOTCH3 pathway is catalogued in Reactome (ID: R-HSA-9017802) and involves 6 genes. In the BiohacksAI corpus, 1 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include APH1A, APH1B, NCSTN, PSEN1, PSEN2.