BDNF activates NTRK2 (TRKB) signaling
REACTOME PATHWAYThe BDNF activates NTRK2 (TRKB) signaling pathway (Reactome ID: R-HSA-9024909) involves 1 genes and is affected by 4 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting BDNF activates NTRK2 (TRKB) signaling
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Sorafenib | — | 300 |
| 2 | Crizotinib | — | 298 |
| 3 | tyrosol | — | 300 |
| 4 | sp600125 | — | 117 |
About the BDNF activates NTRK2 (TRKB) signaling Pathway
The BDNF activates NTRK2 (TRKB) signaling pathway is catalogued in Reactome (ID: R-HSA-9024909) and involves 1 genes. In the BiohacksAI corpus, 4 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include NTRK2.